NME7 Antibody, FITC conjugated

Code CSB-PA897289LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NME7 Polyclonal antibody
Uniprot No.
Target Names
NME7
Alternative Names
MN23H7 antibody; NDK 7 antibody; NDK7_HUMAN antibody; NDP kinase 7 antibody; nm23 H7 antibody; nm23-H7 antibody; NME/NM23 family member 7 antibody; Nme7 antibody; Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase) antibody; Nucleoside diphosphate kinase 7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nucleoside diphosphate kinase 7 protein (1-150AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Gene References into Functions
  1. Study provides evidence that the deleterious mutation in NME7, which results in deletion of amino acids necessary for its interaction with Gamma-tubulin ring complex associated with impaired left-right asymmetry manifested by Situs Inversus Totalis. PMID: 27060491
  2. RNA-seq analysis shows vast differences between the parent FGF2 grown, primed state cells, and NME7AB converted cells, but similarities to altered gene expression patterns reported by others generating naive-like stem cells via the use of biochemical inhibitors PMID: 26749426
  3. NME7 functions in the gamma-tubulin ring complex in a kinase-dependent manner to facilitate microtubule nucleation. PMID: 24807905
  4. Compared with wild-type betagamma nucleoside diphosphate kinase overexpression of Gbeta nucleoside diphosphate kinase suppressed basal cAMP formation up to 55%. PMID: 17363702
Protein Families
NDK family
Database Links

HGNC: 20461

OMIM: 613465

KEGG: hsa:29922

STRING: 9606.ENSP00000356785

UniGene: Hs.706952

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